Gold Posted August 21, 2016 Posted August 21, 2016 Aubrey de Grey Announces Progress in MitoSENS https://www.youtube.com/watch?v=-teTeyUPsJM ^Awesome news from the genetic bio-medicine battlefield front. My personal respect to the scientists fighting human diseases and disabilities day and night, is literally infinite. I am proudly donating to their research and will continue to do so in the light of this incredible success. This particular news is significant because mitochondria is part of human cells that produces our energy like little power-stations, using oxygen we breathe in, but the side-effect is damage from this ongoing chemical reaction of energy synthesis. (Usually called in popular culture as "free-radicals" oxidative damage.) The area of the cell taking most stress is where energy production happens - mitochondria. Mitochondria health is important because it houses a few of our genes we do not want damaged. To make a simplified example: whales live twice human lifespan (!!) because they breathe less than us allowing for less damage from oxygen. This news shows that we should be able to fix free radicals oxidation damage problem by transferring our genes from the mitochondria into the nucleus (central part) of our cells, which is farther away from where oxygen processing in the cell happens, making human genes less susceptible to damage. As biotech is becoming a wide-spread knowledge these days, do not fall behind in fundamental understanding of how human body works! Learn more at http://www.sens.org/
Caley McKibbin Posted January 10, 2017 Posted January 10, 2017 I heard about that idea from him a while ago, but it's beyond my comprehension how that can be done on a mass scale. I vaguely recall reading about the citric acid cycle in a biochem book when I was 12 or so.
A4E Posted January 10, 2017 Posted January 10, 2017 I don't know the details, or watched the video yet. (can not now). But it sounds like from your post that they assume that evolution has been unable to come up with this solution to oxygen based lifeforms. I would rather assume that evolution did not apply the method, because it did not work (well). Do they talk about that in the video? And how is 'moving' the dna going to affect cell divisions / productions?? Or do they never hope for a modified cell to be able to divide? If these questions are adressed in the video, then nevermind.
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